Setup autoconfigure

Is it possible to setup ZxMobile so that the autoconfigure function will work? or does a user always have to manually enter the config info on their device?

In my case, I have webmail configured, so that Web Hosting by MyDomain - WebMail Login auto-redirects to https://webmail.mydomain.com through an apache front end server acting as a proxy.

I am thinking I need to setup something in DNS, both on the internal and external sides, but unsure of what I would need.

Any help appreciated.